'CHAOS AND INFIGHTING'
Iraq's current political class is drawn mainly from powerful Shi'ite politicians, clerics and paramilitary leaders including many who lived in exile before a U.S.-led invasion overthrew Sunni dictator Saddam Hussein in 2003.
Sistani, who only weighs in on politics in times of crisis and wields huge influence over public opinion, on Friday warned against an explosion of civil strife and tyranny. He urged government forces to stop killing protests and protesters themselves to reject all violence.
The government "appears to have been unable to deal with the events of the past two months ... parliament, from which the current government emerged, must reconsider its choices and do what's in the interest of Iraq," a representative of Sistani said in a televised sermon.
Protesters "must not allow peaceful demonstrations to be turned into attacks on property or people," he said.
Wednesday's attack on the Iranian consulate in Najaf set off a sharp escalation of violence.
On Thursday, security forces shot dead 46 people in another southern city, Nassiriya, 18 in Najaf and four in Baghdad bringing the death toll from weeks of unrest to at least 417, most of them unarmed protesters, according to a Reuters tally from medical and police sources.
Clashes between protesters and security forces broke out early on Friday in Nassiriya killing three people and wounding several others, hospital sources said.
Iraq's "enemies and their apparatuses are trying to sow chaos and infighting to return the country to the age of dictatorship ... everyone must work together to thwart that opportunity," Sistani said, without elaborating.